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The assistance stage continued throughout the follow-up period. In the first intervention week after the agreement stage, a 36 week follow-up phase began that was conducted in two phases over a period of 12 weeks (intervention period) and 24 weeks (follow-up after intervention). During the first 12 weeks, the patient's progress was checked by telephone once a week. To establish continuous interaction, the telephone number of the researcher was provided to the patients. Patients were also visited every 4 weeks. During the monthly visit sessions that lasted about half an hour, the practical programs and related Docetaxel price checklists were examined and necessary changes in objectives and practical programs, if needed, were made upon a further agreement. In the 24 weeks follow-up after intervention, a monthly communication with patients was made by telephone to evaluate the feedback of training, and provide necessary instruction. Whenever an unplanned visit was needed, the researcher was present at the clinic. Statistical Analysis: The obtained data were entered into the statistical software SPSS v.19. We used descriptive statistics to determine the frequency, mean and standard deviation, and paired t-test and Wilcoxon test to compare the mean score of eight dimensions and the total QoL score before and after the intervention. The Hotelling's T-squared multivariate test was also applied to compare the structure of life quality before Vatalanib (PTK787) 2HCl and after the intervention. The repeated measures test was used to compare the eight dimensions and the total QoL score at the baseline, twelfth and thirty-sixth week of the intervention. Results Based on the study findings, the average age of participants was 25.84��7.23. There were 52 women (75.4%) and 17 men (24.6%). Other demographic information is shown in Table 1. Table I Descriptive www.selleckchem.com/products/EX-527.html data for demographic variables The comparison between the QoL scores in patients with sickle cell disease before and after the intervention revealed that the mean score of eight QoL dimensions as well as the total QoL score after intervention had increased compared to those before the intervention, and paired t-test and Wilcoxon test indicated a significant difference (P