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Both facilities are tertiary care hospitals that treat ROP cases referred from the entire country. The research committee and biomedical ethics unit at King Abdulaziz University Hospital approved this study. Inclusion criteria were, all infants Luminespib price who born ?32?weeks gestational age and/or birth weight ?1500?g. Infants born before 27?weeks were screened at 30�C31?weeks postmenstrual age (PMA). Infants born after 27?weeks or weighing selleck chemicals llc factors (Table 4). The risk factors that were assessed were, intraventricular hemorrhage, patent ductus arteriosus (PDA), sepsis, and hydrocephalus. The infants were assessed regularly until the retina was fully vascularized. Treatment was performed within 72?h of diagnosis. Infants who did not require laser treatment underwent routine vision screening, unless there was a specific concern. The indications for treatment of severe ROP were: zone I, any ROP with plus disease; zone I, stage 3 without plus disease; zone II, stage 3 with plus disease or; zone II, stage 2 with plus disease.5 Table 4 Risk factors for retinopathy of prematurity in the study group and a control group. Statistical analysis The data were collected for statistical analysis and entered into the statistical package for social sciences (IBM Corp., Armonk, NY, USA). The relative risk was used to measure the risk and logistic regression was used to adjust for confounding factors. A p value less than 0.05 was considered statistically significant. Results Ninety-two premature infants were screened for ROP. There were 31 (33.7%; 16 females and 15 males) infants diagnosed with ROP and 12 (13%) Fleroxacin infants required laser treatment. The mean gestational age was 26.7?weeks (range, 24?weeks to 29?weeks) and the mean birth weight was 0.843?kg (range, 0.606�C1.450?kg). There were fourteen (45.2%) infants with stage 3 ROP which was the most common type of ROP in this study (Table 1). The majority of cases (20 infants; 64.5%) were found in zone 3 (Table 2). The fewest cases of ROP were in zone 1 (2 cases; 6.5%) (Table 2). All cases needing treatment received laser therapy within 72?h of diagnosis (Table 3).

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