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Secondary end-points include individual components of MACE and target lesion thrombosis. Death from CVS causes was defined as death due to acute MI, cardiac perforation or tamponade, arrhythmia, a complication of the PCI procedure or as any death in which a CVS cause could not be ruled out. Target-vessel related MI was defined as the presence of new Q waves in at least 2 contiguous leads on electrocardiogram (concordant with the intervened target lesion) with elevation in cardiac troponin or in creatine kinase/creatine kinase-MB above the upper limit of the normal range, or in the absence of pathologic Q waves, MI was diagnosed in the presence of an elevation in cardiac troponin or in creatine kinase?>?2 times the Flavoprotein upper limit of normal. TLR was defined as any repeat revascularization (percutaneous or surgical) secondary to a stenosis?>?50% within the stent or within 5?mm proximal or distal to the stented segment. Target lesion thrombosis was defined according to the Academic Research Consortium [13] criteria for definite and probable stent thrombosis. In our study, we defined native coronary artery as small vessel when reference vessel diameter?��?2.8?mm and as de novo learn more lesion when reference vessel diameter?>?2.8?mm. Our retrospective study conforms to the ethical guidelines of the 1975 Declaration of Helsinki and was approved by the institution's human research committee. Continuous variables were expressed as mean?��?standard error of mean. Dichotomous variables were expressed as counts and percentages. Statistical comparisons were performed using Student��s t test or Fisher��s exact test, as appropriate. Multivariate regression analysis was performed ( using an enter regression model) to evaluate predisposing factors for TLR, in which each entered variable had p value?check details were considered statistically significant. Table?1 show the baseline clinical characteristics of the study patients. The mean age of the patients at presentation was 61.3?��?11.2?years with male preponderance (76%). Diabetes mellitus (DM) was present in 155 patients (48.4%) and 137 patients (43%) had history of prior stenting. The mean left ventricular function was 45?��?13 %. The majority (76%) of patients presented with acute coronary syndrome (ACS). Table?2 shows the angiographic features and procedural data of our patients. The majority of patients (78 %) had multi-vessel disease on coronary angiography. The most common target vessel for PCI with DEB was left anterior descending artery (37%), right coronary artery (18%), left circumflex artery (17%) and others (28%).
