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7%, which might explain the low sarcoidosis ratio. The studies in the literature point to higher ratio for sarcoidosis than for IPF, which is in line with the findings of our study. The sarcoidosis ratio reported by the Germany study is similar to our ratio. The IPF ratio reported in Flanders and Greece is also close to the ratio our study reports. The difference between the data reported in previous studies and ours can both be attributed to geographical Ruxolitinib in vitro distinctions and to differences in the methods used. The number of cases registered in the present study was considerably high compared to the previous studies. Furthermore, data reported by primary care physicians are included in some of the mentioned studies, while in our study, contribution is restricted only to pulmonary specialists with experience in ILD resulting in more reliable data. Pneumoconiosis Vemurafenib molecular weight cases and exposure to other inorganic dust and gases constitute 12% of the cases. Silicosis was the most frequent disease among pneumoconiosis, probably because of the increase in denim sandblasting, which is an occupational disease, in the last decade in Turkey. This registry was done during this period. Fortunately, severe precautions had been recently taken in the working places to prevent the increase of this devastating disease. Therefore, the high silicosis ratio reported in this study can be interpreted as being specific to the period of analysis of the present study. This interpretation warrants Amiloride further prospective studies on the denim sending and silicosis. Cases with CTD, constituting 10% of all the diagnosable cases, together with drug-induced cases and radiation fibrosis cases, one fourth of all the cases can be diagnosed by a careful medical history. The ratios of diseases change considerably with respect to age and gender. For females, 53% of the patients has sarcoidosis, while this ratio reaches 75% for women under the age of 50 years. For this group, IPF ratio is just a 3%. In contrast, the IPF and sarcoidosis ratios were equal in males (25%). For men over 50 years, sarcoidosis ratio was just 8%, while IPF ratio was 45%. Although diagnostic criteria including age and gender were removed from the recent IPF guideline of ATS/ERS, age and gender still seem to be important factors in the differential diagnosis of sarcoidosis and IPF [18]. The subgroups of idiopathic interstitial pneumonia were as follows: 81.1% IPF, 4.2% nonspecific interstitial pneumonia (NSIP), 10.7% COP, 1.8% desquamative interstitial pneumonia (DIP), 0.4% respiratory bronchiolitis associated interstitial lung diseases (RB-ILD), 1.2% lymphoid interstitial pneumonia (LIP) and 0.6% acute interstitial pneumonia (AIP) cases. In the literature, these ratios are reported to be: IPF 47%�C64%, NSIP 14%�C36%, COP 4%�C12%, DIP and RB-ILD sum 10%�C17%, LIP 1% and AIP?