Values above connecting lines indicate a significant difference between MWCNT and HDM/MWCNT treatment

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Cytospins of BALF showing GW274150 neutrophilic inflammation with MWCNTs alone and mixed neutrophilic/eosinophilic inflammation with MWCNTs soon after HDM sensitization. 871361-88-5 Photographs taken at 100X magnification. Effect of HDM sensitization and MWCNT exposure on allergic inflammation and inflammasome activation. (A) Representative hematoxylin and eosin (H&E)-stained lung sections from mice sensitized with HDM and exposed to MWCNTs for 1 day. Images taken at 10X magnification. (B) Qualitative inflammation scoring for mice sensitized to HDM and exposed to MWCNTs at 1 and 21 days. Lung sections from each treatment group scored in a blinded fashion according to severity of inflammation. Statistical analysis performed using a one-way ANOVA with a post-hoc Tukey for comparison within timepoints, and using a two-way ANOVA with Bonferroni post-tests for comparison between timepoints. P

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