The Uncomplicated Truth On Unoprostone

RESULTS Ages ranged from 6 months to 9 years (mean 4.6 �� 2.8) with six males and one female. There were three bilateral cases with total 10 lesions. Mean operating time was 39.8 �� 12.5 minutes (range 25-65 minutes) per stoma. There was no major intraoperative complication. Except for peri-stomal excoriations no major complication occurred postoperatively. Ureteric reimplantations were successfully done in all the seven cases 6 - 12 months after ureterostomy needing tapering in one case. Mean follow-up was 1.7 �� 8 years (range, 6 months to 2.5 years). Renal functions were improved in six cases in terms of serum creatinine and isotope renogram studies and one patient deteriorated after reimplantation [Table 1]. Table 1 Demography and outcome measures DISCUSSION Laparoscopy, these days is a well-accepted modality in the treatment of a wide range of surgical problems in children.[10,11,12,13,14,15] Selleckchem BGJ398 The truth is, diagnostic laparoscopy for impalpable testes was the fore-runner of paediatric laparoscopy and now laparoscopy is also widely practiced in other fields of paediatric urology.[16,17,18,19,20,21,22,23,24,25] Laparoscopic Protease Inhibitor Library chemical structure cutaneous ureterostomy can be done either by retroperitoneoscopy or by transperitoneal route and retroperitoneoscopy has the advantage of avoiding possible intra-abdominal adhesions while transperitoneal approach facilitates bilateral procedures.[24,26] Cutaneous ureterostomy has its own complications including failure, ureteral hernia, retraction and stenosis, acute pyelonephritis and deterioration in renal function.[3,7,8] Laparoscopy reduces the risk of hernia, retraction and stenosis by its minimal damage to the abdominal wall layers during procedure.[4] We did not find any of these complications in our series except persistence of urinary infection in two cases for more than 1 month. However, peri-stomal excoriation developed in all cases which persisted until reimplantation in two cases. We have managed this excoriation applying zinc oxide paste and a pad of soft clothe was applied over that to absorb the urine which was changed frequently. Unoprostone All of our patients were improved clinically and with normal creatinine level (