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In the remaining 35 patients, one hundred sixteen endosseous titanium implants were simultaneously placed. Follow-up time varied between 6 and 144 months (mean 52.4); of these, 36% were followed up for periods of time longer than 60 months. Implant diameter and lengths varied between 3.3 to 4.8 and 12 to 16?mm, respectively. In the 35 successful procedures (one hundred sixteen implants), the overall implant survival rate was 100%. An average gain in ridge width was 3.5?��?0.93 (p?Ritonavir of this study, we suggest that the combined osteotome-induced ridge expansion and guided bone regeneration simultaneous with implant placement is a reliable procedure with reduced morbidity and may offer an alternative in suitable situations. ""Purpose: The aim was to document the Nobelreplace tapered TiUnite? (Nobel Biocare, G?teborg, Sweden) implant system used by experienced clinicians in daily practice for replacing single maxillary anterior teeth and to compare the clinical and radiographic outcome learn more between implants installed in healing sites (early implant placement) and fully healed sites (conventional implant placement) after on average Dabrafenib two and a half years of function. Material and Methods: A cross-sectional study in patients who had been treated by two periodontists and two prosthodontists in 2006 and 2007 was conducted. Surgical treatment involved standard flap elevation without releasing incisions and restorative procedures included cemented crowns in all patients. Only straightforward single implant treatments in healing sites (6�C8 weeks following tooth extraction) and fully-healed sites (��6 months following tooth extraction) were considered with both neighboring teeth present and without the need for hard and/or soft tissue grafting. Clinical and radiographic analyses of all implants were performed by a blinded clinician who had not been involved in the treatment. Results: Forty-nine of the 53 eligible single implants (22 early and 27 conventionally placed implants) in 44/48 patients were available for scrutiny. There was no significant difference in implant survival between early (95%) and conventionally (93%) installed implants (p?=?1.000). Mean bone level to the implant-abutment interface was 1.25 and 1.02?mm for early and conventional implant placement, respectively (p?=?.220). In spite of fairly low plaque levels (26%), overall peri-implant bleeding was quite prevalent (36%). Mean peri-implant probing depth was 3.3?mm. Five restorations had experienced technical complications.