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Results Study population and the stool samples Over the 34 month period from January 2008 through October 2010, there were a total of 571 cases of AGE admitted to the QEH. This accounted for 11% of all medical hospitalization among the children in Barbados. From among the 571 children with AGE admitted to the QEH, stool culture results were recorded for 266 (46.6%) cases. The age and gender distribution of the all the children with AGE admitted to the QEH and those that had a documented stool investigation results are shown in Table 1. Overall 245 (42.9%, 95% Confidence Interval �C 38.8%, 47.1%) children were 12 months or younger and 370 (64.8%, 95% CI �C 60.8%, AR-42 datasheet 68.8%) children were 24 months or younger at the time of admission for the AGE. Female to male ratio was 1:1.4. The overall annual incidence rate of severe AGE requiring Inulin hospitalization was 4.1 (95% CI �C 3.6, 4.7) per 1000 under 15 children per year. The annual incidence rate for severe AGE for children under 5 years was 26.8 (95% CI �C 24.4, 29.4) per 1000 under 5 children. An analysis of the seasonality in the occurrence of severe form AGE in children requiring hospitalization revealed multiple peaks (Figure 1). Cases of AGE peaked during the month of June with two other smaller peaks in the months of February and October. October November is the hot and wet season in this country. Figure 1 Seasonal distribution of all the cases of childhood AGE hospitalized in Barbados. Table 1 Basic Demographic profile for children hospitalized with AGE. Isolation and Identification of Pathogens Of the 266 children with documented stool test results, stool tests were positive for an enteropathogen in 98(36.8%, 95 Confidence Interval �C 31%, 43%). Among the 218 children Epigenetics Compound Library as an etiological agent in 24 cases (9.0%, 95% CI �C 6.0%, 13.3%). Of the 56 children who had non-typhoidal salmonella gastroenteritis, 54(96.4%) were younger than 5 years. Figure 2 shows the age distribution of salmonella and rotavirus enteritis in children less than 5 years. Non-typhoidal salmonella species peaked in the first year of life while Rotavirus enteritis peaked in the second year of life (Figure 2). Of the 34 staphylococcal isolates, 30 were isolated from the samples where salmonella species were also isolated and 2 were isolated from samples where campylobacter was isolated. Figure 2 Age distribution of cases of salmonella and rotavirus acute gastroenteritis among children