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The management table and the curriculum overview are publically available on the resources page of the Project SEMILLA website (available from: http://www.projectsemilla.org). When piloted in 2013, knowledge of the core concepts of resuscitation Decitabine cell line improved. On a multiple-choice exam of the concepts of resuscitation, the median pre course score was 24% (interquartile range 20-32%) and improved post course to 68% (interquartile range 64-76%) (PTryptophan synthase performance of a set of predetermined actions. Setting The setting of the research was at Hospital Escuela Oscar Danilo Rosales Arg��ello (HEODRA), the teaching hospital of the medical school of Universidad Nacional Aut��noma de Nicaragua (UNAN) in Le��n, Nicaragua. It is a 400-bed tertiary referral center that services the population of Northwest Nicaragua with multiple residency programs. The hospital has an Intensive Care Unit (ICU) and sees an average of 300 emergency department visits per day. The pre-course assessment, resuscitation course participation and immediate post course assessment were all completed during February, 2014. The 6 month post PD98059 course assessment was completed in August, 2014. Subjects In total, we were able to retain 13 of 15 initial subjects and 13 completed the simulation at all three study time points. Attrition of the 2 subjects was secondary to call schedules that did not allow them to participate in the final simulation. These residents have completed a medical degree and are now enrolled in post-graduate training at UNAN in internal medicine, surgery, gynecology, anesthesia, and pediatrics. Their average age was 28.5 years-old and standard deviation was 3.3 years-old. Their other characteristics are presented in Table 1. Table 1.