The Main Tubulin Entice

The use of propofol for routine GIE procedures also is not recommended by American Society of Gastrointestinal Endoscopy[31]. Generally, the registered nurses administered propofol sedation is selleckchem cost-effective. Several studies have been demonstrated the safety and efficacy of the registered nurses administered propofol sedation. For example, the study of Rex et al[32] demonstrated that the registered nurses and endoscopists could safely administer the propofol for GIE endoscopy[32]. Additionally, several data were also confirmed these in the invasive GIE procedures including ERCP, EUS and balloon endoscopy[33,34]. Moreover, the safety of nurse-administered propofol sedation in an ambulatory center also confirmed by the report of Walker and colleagues[35]. This report described the authors�� experience in 9152 GIE procedures. The sedation-related adverse events were observed in seven patients including laryngospasm, apnea and pulmonary aspiration and all related with upper GIE procedures. However, tracheal intubation was not needed in all these cases. To date, no clinical studies are directly compared between the registered nurse and gastroenterologist or endoscopist-administered sedation for GIE procedures. The administration of propofol by registered nurse is usually performed under direct supervision of the physician. The safety profiles of this sedation technique by the registered nurse for GIE procedures were evaluated in 27500 patients. Tubulin NLG919 cell line Among these patients, 6.7% developed hypoxemia (SpO2 required oxygen supplementation. Severe hypoxemia (SpO2