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Hydrodissection was performed with caution in FLACS patients to avoid capsular block syndrome. In the conventional surgery group, the capsulorrhexis, nuclear division and corneal incisions were performed manually. The remainder of the surgery was performed in the standard fashion. Surgery start time was defined as the time that the patient arrived in the operating room. this website The end of surgery was defined as the time that the patient was moved out of the operating room. Routine preoperative parameters were visual acuity, intraocular pressure, anterior segment and fundus examination. Preoperative and postoperative visual acuity was evaluated as presenting and the best-corrected visual acuity (BCVA). Complications during surgery such as capsular rupture, Megestrol Acetate lens dislocation and wound leak were noted. Corneal edema, lens dislocation, wound leak, endophthalmitis and retinal detachment were among the complications noted at 24 h following surgery. The surgeons were particularly vigilant for capsular rupture at the beginning of the case caused by expanding gas bubbles from lens division. They also observed eyes carefully for signs of capsular block syndrome. This would have occurred during hydrodissection due to the expanded size of the nucleus from gas bubbles formed during lens division. This larger nucleus would not allow escape of irrigated fluid, causing the building up of pressure at the posterior capsule resulting capsular rupture. Ruptures identified at entrance to the anterior chamber or immediately after hydrodissection were defined as complications of the femtolaser treatment. Demographic data included gender and age of the patient. Clinical information included eye operated, ocular comorbidity, type of cataract, systemic comorbidity and intraocular pressure (IOP). Intraoperative data were collected on anterior capsular tear, difficulties in nuclear fragmentation, posterior capsular tear, zonular rupture, etc. Postoperative data collected within the 1st postoperative week included wound leak, corneal edema, IOP, anterior chamber reaction, centration of the IOL, status of the anterior capsulotomy, pigment dispersion, posterior capsule status; other complications or morbidity. The identity of surgeon and patient were removed during for data collection from patient charts. Postoperative Birinapant concentration information at 6�C8 weeks postoperatively included presenting visual acuity and the BCVA, corneal status, anterior chamber reaction, IOL centration, complications if any and the cause of ventriculo-atrial of
