The Good, The Unhealthy Along with Hydroxychloroquine

, Chicago, IL, USA). Qualitative data were presented as number and percentage. Survival curves were estimated by the Kaplan-Meier method with log rank test to assess significance. Multivariate Cox proportional hazard regression models were used to evaluate any independent prognostic effect of the variables with 95% confidence interval (CI). A P-value of features of all thyroid carcinoma patients Prognostic features of PTC Our results showed that old age, large primary tumor Oxygenase size, lymph node stage, extrathyroid extension, and DM were significant poor prognostic factors for PTC on the univariate analysis of OS (Table 2). Multivariate COX hazard analysis showed that patient age (HR =5.94; 95% CI, 1.237-28.650; P=0.026), extrathyroid extension (HR =3.527; 95% CI, 1.070-11.626; P=0.038), and DM (HR =12.968; 95% CI, 3.924-42.854; PFasudil supplier factors in the PTC patients�� series in relation to DFS using log rank test are summarized in Table 2. Our results showed that male gender, old age, large primary tumor size, lymph node metastasis, extrathyroid extension, and multifocality were significant poor prognostic factors, but the multivariate COX hazard analysis showed that tumor size (HR =3.972; 95% CI, 1.237-15.650; P=0.023) and lymph node stage (HR =5.434; 95% CI, 1.245-26.530; http://www.selleckchem.com/products/hydroxychloroquine-sulfate.html P=0.014) were the only independent prognostic factors (Table 3). Table 2 Prognostic variables in PTC in relation to OS and DFS Table 3 COX proportional hazard analysis of the predictors of DFS in the PTC series We studied the differences in survival between the various types of PTC in terms of the OS and DFS, and no significant relationship was found [OS (LR =3.788, P=0.150) or DFS (LR =0.798, P=0.671)]. Prognostic features of FTC We found that the only factors that significantly affected the OS of FTC patients were DM and degree of tumor invasion (Table 4). However, none of these remained independent in the multivariate analysis. The factors that affected the DFS of FTC on univariate analysis are summarized in Table 4. The results showed that tumor size, extrathyroid extension, and degree of tumor invasion were the only significant poor prognostic factors in FTC patients. Only extrathyroid extension (HR =10.956; 95% CI, 2.724-39.864; P