Since mTOR signaling pathway is involved in synaptogenesis, another possible side effect of rapamycin may be its impact on cognitive function

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Rats ended up sacrificed right after four months of treatment and the ratio of spleen to entire body bodyweight was calculated. Rats treated with one. and three. mg/kg exhibited the ratio lower. C. Rats were sacrificed soon after 4 weeks of treatment method and the ratio of Finally, we evaluated its effect on growth, development, immunity and cognition after a relatively long term administration of rapamycin in young rats thymus to entire body weight was calculated. A diminished ratio was also located in rats treated with 1. and three. mg/kg rapamycin. p

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