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Data were collected during several community health screenings attended by at least one of the authors. Booths were set-up at health fairs and anyone could approach for testing free of charge. Most of the health fairs were conducted in areas of high concentrations of Cuban Americans. Cuban Americans are dissimilar from Mexican Americans in that they are of Caucasian heritage instead of native Central American (e.g. Mayan, Aztec). The research project was reviewed UGT1A7 and approved by the Institutional Review Board of ��blinded�� University. Each subject self-reported gender, age, and ethnicity. In addition, the health screener visually confirmed the gender and ethnicity reported by the participants. Bone density measurements were performed on each subject��s non-dominant heel by asking each subject which hand they write with. Measurements Crizotinib manufacturer were taken using a Hologic Sahara Bone Sonometer by individuals who had received training in the proper use of the bone sonometer. T scores were obtained directly from instrument readings subsequent to calibration; data were entered into Microsoft Excel by two of the researchers. Descriptive, as well as, inferential statistics were used to analyze the data. An independent t-test was used to determine statistically significant differences between the groups and subsequent correlation analysis was performed to investigate the relationship between T scores and age. Stepwise regression analysis was used to obtain the impact of ethnicity independent of age effects. All statistical analyses were carried out using SPSS version 14.0. RESULTS Four hundred and four total bone density measurements were performed. Data are presented for 352 women of which 209 were Hispanic and 143 were non-Hispanic whites. Excluded from this analysis were results from males and women of other ethnicities. Study participants ranged from 55 to 97 years of age with a mean of 70.1 (SD=9.8). The mean age of Hispanics was 68.5 (SD=8.5) years, while the mean age of non- Hispanic white was 72.4 (SD=11.1) years (t= -3.88, pR428 research buy sample was -1.23 with a standard deviation of 1.04. The mean T score obtained for Hispanic women was -1.194 (SD= 0.93) and -1.280 (SD= 1.18) for non-Hispanic white women. The regression coefficient for the linear regression employing both age and ethnicity was non-significant for ethnicity (t = 0.60, p = 0.55). A retrospective statistical power analysis revealed greater than 90% power to detect a change in R2 of 0.05. DISCUSSION The results suggest that women in this study, regardless of ethnicity, are at comparable risk of developing osteoporosis.

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