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The study included 38 patients coinfected with HIV and CHC who were injecting drug users. To draw a comparison of immunological indices, 36 patients with HIV/CHC but not injecting drug users were concurrently examined. In patients who used injecting drugs, only an intravenous injection of drugs was marked; however, the abuse drug by the intranasal route was not defined. The abuse drug by the intranasal route was not marked in patients who were not injecting drug users. The patients�� description is presented in Table 1. In general, the study groups were comparable (P>0.05). Table 1 Characteristics of coinfected HIV/CHC patients The average age of injecting drug users with HIV/CHC was 31.1��0.6 years (median 30.0 years) while the average age of patients with HIV/CHC but not PFKM injecting drug users constituted 33.4��0.7 years (median 33.5 years). Sex composition of the group featuring injecting drug users with HIV/CHC consisted of 32 males (84.2%) and six females (15.8%). The sex distribution of the group of patients with HIV/CHC but not injecting drug users had a ratio see more of 29 (80.6%) versus seven (19.4%), respectively. Our study was conducted prior to the therapy. Moreover, the patients essentially were in stage I and II of HIV infection without clinical CHC, and they had early stages of fibrosis. It should be noted that patients coinfected with HIV/CHC require individual approach that will take into account their state of immunodeficiency. Patients were followed up in view of their further selleck compound treatment. Highly active antiretroviral therapy (HAART) was prescribed for HIV/CHC coinfected patients with number of CD4-lymphocytes