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05. All www.selleckchem.com/products/cobimetinib-gdc-0973-rg7420.html data are means �� SEM. Fetal arterial pH, blood gases, lactate and glucose values are shown in Table 1. There was a significant overall fall in fetal arterial partial pressure of O2 with gestation, and fetal glucose values were lower at 0.8 ga than at 0.6 or 0.7 ga. In 0.8 ga fetuses, atropine infusion was associated with a small increase in fetal lactate levels but no other change. There was no effect of 6-OHDA. Fetal heart rate fell progressively with advancing gestational age (P= 0.005; Fig. 1). At all ages, power was greatest in the VLF band, with relatively little power in the HF band [P GABA receptor activation but not the HF band, was significantly higher at 0.8 ga than in the younger groups (P bars). Atropine infusion was associated with a switch to HV sleep, which was maintained during the infusion. Fetal heart rate was significantly increased during atropine infusion, compared with HV sleep (P ALG1 during the infusion (P= 0.05, F= 6.3, d.f. = 5), with no interaction with frequency band (P= 0.6, F= 3.9, d.f. = 10) and, correspondingly, no significant effect on the LF/HF ratio in HV sleep (Fig. 2, middle panel; HV sleep during atropine infusion, filled bar). 6-Hydroxydopamine was associated with a significant reduction in FHR in HV sleep (P