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In a subset of subjects we additionally recorded psychophysiological parameters, results of which will be presented elsewhere. Visual duration reproduction �C short Similar to the two versions with longer intervals, a visual (but not auditory) duration reproduction task with stimulus duration of 600, 800, 1000, 1200, and 1400 ms (with eight trials per interval presented in randomized order) was employed with a green and yellow square marking the two intervals and with pause intervals Selleck VX809 of 1.5, 2.75, 2, 2.25, or 2.5 s in between. No secondary working-memory task was presented for these short stimuli. Subjects were requested to stop the second yellow square by pressing the space bar when subjects felt that it had reached the duration of the first green square. The attention network test (ANT) The ANT (Fan et al., 2002) assesses the processing efficiency of the three attention networks of (1) alerting, (2) orienting, and (3) executive attention. They are quantified by means of computerized reaction time measures for differently Histone demethylase cued and un-cued stimulus conditions with or without presented flankers. In essence, the ANT is a combination of a cued reaction time task and a flanker task, where cues can facilitate reaction time and flankers can either facilitate or impede reaction time. Participants have to respond to either the left or right arrow key on the computer keyboard depending on the stimulus configuration, the target stimulus being an arrow pointing to the left or right AG-14361 order and flankers being either congruent (facilitating) or incongruent (impeding). An overall reaction time score and an index of accuracy are also calculated. STATISTICAL ANALYSES t-tests for group differences are employed and one-factorial ANOVAs for group differences with the two factors of ��group�� and the different ��time intervals�� in the duration reproduction tasks. For multiple comparisons alpha level adjustments according to the false discovery rate method (FDR; Benjamini and Hochberg, 1995) was applied for each measurement and inventory with initial significance levels set to p

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