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We do not know the exact reasons. However, we suggest possible explanations; 1) we included the patients with successfully reperfused by either PCI or thrombolysis, buy Ion Channel Ligand Library and therefore, LV volume was not larger than normal population in Korea.29) This may be related with more chances to get reverse remodeling in patients with larger LV volume. 2) Strict medication could be another cause of reverse remodeling. Core measure of Korean Health Insurance Review and Assessment Service forced to treat dual antiplatelet therapy, statins, beta-blockers, and renin- angiotensin system blockade in all STEMI patients, which was related that patients who had larger LV volume had more chances to reverse remodeling. Limitations We should consider some limitations of the study. It should be taken into account that it was a retrospective analysis, PIK-3 leading us to consider a selection bias. This study result cannot apply to all AMI group because we targeted only low risk STEMI patients. Considering that the echocardiography was done 24 hours after revascularization, it can be assumed that myocardial stunning might affect initial echocardiographic data. Thus, it might be different from the echocardiographic data after myocardial recovery. Although GLS had a prognostic power to predict remodeling in STEMI, area under curve for remodeling was only 0.62 (95% CI: 0.53�C0.71). The best cutoff value does not have a high sensitivity and specificity for remodeling. Although the quality of 2D speckle tracking imaging was quite clear, higher resolution for cardiac border is still needed. Lenvatinib manufacturer Also automated speckle tracking analysis can be possible through dedicated software. Furthermore, the border tracing needs manual work, hence intra- and inter-observer error was unavoidable. The development of speckle tracking is rapidly progressed. 3D speckle tracking may overcome many drawbacks of 2D strain in the near future.30) Conclusion In this research, we demonstrated GLS as a predictive parameter of future adverse remodeling. It seems that GCS or torsion was not significant in STEMI patients with low risk group. Acknowledgements This study is supported by grant No. 02-2013-111 from the SNUBH Research Fund.""According to simply logistic regression analysis, the marginally significant baseline clinical and laboratory covariates including age, gender, smoking status, hypertension, total cholesterol, HDL cholesterol, low density lipoprotein cholesterol, hemoglobin, T2DM, and NLR were entered into a multivariable logistic regression model (Table 2). According to the final model selected in stepwise fashion, both NLR [adjusted odds ratio (OR), 1.25; 95% confidence interval (CI), 1.13�C1.4; p