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The disease occurred in all age groups, but in 78.7% (100/127), it was between 41�C80 years. The population consisted of 68 males (55%) and 56 females (45%) (ratio 1.2/1). Gender was not available for 26 patients. All patients with YNS and PE had lymphoedema, while 14.4% (18/125) did not have yellow nails.[2, 4, 7, 15, 19, 20, 25, Entinostat nmr 35, 47, 56, 67, 74, 87, 107] PE was bilateral in 95 patients (68.3%), right-sided in 20 and left-sided in 17. In the other seven, PE was unilateral (not stated whether right or left), and 11 did not specify whether it was unilateral or bilateral. In the 85 cases of patients with PE and descriptions of its appearance, 64 (75.3%) were serous, 17 milky, (16 chylothorax[17, 38, 42, 47, 59, 64, 74, 75, 86, 88, 99, 108] (18.8%), one pseudochylothorax[91]) and three empyemas.[11, 52, 110] A single patient with bilateral PE presented with a milky appearance on the right and serous on the Mianserin HCl left.[112] The PE was described as an exudate in 54 patients (94.7%) and a transudate in three patients (5.3%).[17, 90, 112] PF culture was positive in four cases for anaerobic streptococcus and fusobacteria,[28] streptococcus pneumoniae,[52] escherichia coli[56] and Pseudomona Aeruginosa.[110] Cytology was negative for malignancy in 59 patients in which it was described and pleural biopsy was normal or did not provide any further diagnostic information in 10 cases;[2, 4, 14, 23, 35, 38, 45, 48, 65] 40 patients showed findings compatible with chronic fibrosing pleuritis, and metastatic melanoma was observed in one SCR7 solubility dmso patient.[63] The nucleated cell count was low (median 1,540 cells/mm3; range 240 to 8,000) with a cell predominance largely lymphocytic (48/50 patients, 96%). In the other cases, the prevalence was polymorphonuclear.[62, 89] Protein levels in the PF were described in 66 patients, while in two cases it was only noted that they were elevated. The median was 4.2?g/dL (range: 1.6 to 9[4]). In 92.4% of patients (61/66), protein values were ��?3?g/dL. The other five cases corresponded to a single transudate (proteins 1.9?g/dL) and the remainder did not specify whether they were exudates or transudates; however, the LDH values in two cases were 315 and 330?IU/L (proteins 2.2 and 1.6?g/dL, respectively) (Table?2).[89, 107] NA NA 6,?100 4,?94 Predominantly lymphocytes: 48/50 cases (96%) Predominantly polymorphonuclear: 2 cases (4%) A transudate with cholesterol value 55?mg/dL LDH values in the fluid were provided in 30 patients, although two only state that they were elevated. Except in one case in which the LDH was 2,609?IU/L,[62] the range of the remaining 27 was 55�C410?IU/L. Pleural cholesterol was determined in 19 patients (the value specified was high in only one). One case was a transudate (cholesterol