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When the PRW group pass rate was compared to the control group, an independent samples t-test was used. Rotation performance was evaluated using the standardized evaluation form completed by rotation preceptors. The responses were evaluated by the study investigators after completion of study follow- up and were categorized as having an either acceptable or unacceptable level of skills for rotations. An acceptable level of skill was defined as an average score of five to seven (overall Protein Tyrosine Kinase inhibitor and within each of the five categories), and an unacceptable level was defined as an average score of one to four. Percentages of students in each category were compared using the independent samples t test. RESULTS A total of sixteen students were recruited from the fourth year of the entry-level Doctor of Pharmacy professional degree program: Eight students (13% R428 clinical trial of the class) in the experimental group and eight students in the control group. Experimental and control group participants were categorized into the low GPA (Experimental=N=1 and control=N=1), moderate GPA (N=3 and 3), and the high GPA (N=4 and 4). All participants in the experimental group completed the PRW, including the OSCE cases both before (case 1) and after the PRW (case 2). All participants in both the experimental and control groups were administered the OSCE case (case 2) both before and after the year of APPE rotations. Twenty-two full-time college of pharmacy faculty completed a total of 47 preceptor evaluations of rotation preparation (completed at the beginning and end of the rotation). All participants were evaluated on at least two clinical APPEs (range 2-5 evaluations conducted per participant, average number of clinical rotations evaluated =2.94). The difference in the experimental group��s performance on an OSCE prior to (38% pass rate) and following (88% pass rate) the PRW was statistically significant (pUGT1A7 an OSCE prior to start of the APPEs (88% pass rate) compared to the control group��s performance (0% pass rate) (p=0.001) measured by the independent samples t-test. However, there was no statistically significant difference in performance on an OSCE after the completion of the APPEs between the experimental (75% pass rate) and control (50% pass rate) groups (p=0.252) measured by the independent samples t-test. No statistically significant difference was found between the experimental and control group��s demonstration of clinical skills during the first week or at the completion of the clinical APPEs (see table 1) as evaluated by the rotation preceptors. Table 1 Clinical Rotations Evaluations. DISCUSSION The PRW was designed to be an introductory APPE for the transition from didactic coursework to clinical APPEs at our institution.