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7 compared to unstimulated cells (P Oxygenase results indicated that RAW264.7 secreted significantly higher levels of IL-12 following IFN-��/LPS stimulation compared to cells without stimulation, but almost with no detectable level of IL-10; however, IL-4 stimulated RAW264.7 barely secreted IL-12 but significantly higher levels of IL-10 (P but almost no expression of Arg-1 gene coding fragments (P (Fig. 1D). Fig. 1 M polarization recognition system adopted in this study. Different antigens of S. japonicum induced M polarization CD16/32 NLG919 order expression increased significantly in RAW264.7 with NCA and ACA stimulation while CD206 expression showed an insignificant difference. CD206 expression increased significantly in RAW264.7 SEA stimulation compared to unstimulated cells (P (P HDAC inhibitor antigens of S. japonicum induced M polarization. M polarization induced by schistosomal infection The highest expression of M1 surface marker CD16/32 appeared at 3 weeks after infection, and gradually declined from 6 weeks after infection (P