Entertaining Tweets Regarding Vatalanib (PTK787) 2HCl

Results?The prevalence of atopy and serum IgE level was significantly lower in elderly group compared with that in young group. The bronchial hyperresponsiveness and reversibility (determined by MCT and BDT) were similar in both groups. In general, patients with bronchial hyperresponsiveness had poor forced expiratory volume in one second predicted value (FEV1 % pred.) and higher proportion of atopy. Elderly asthmatics with atopy had worse FEV1 than elderly non-atopic asthmatics (70.3 % vs. 77.6% pred.). On the contrary, young atopic asthmatics had better FEV1 compared with young non-atopic asthmatics. Young atopic asthmatics were significantly associated with airway hyperresponsiveness than young non-atopic asthmatics (p?=?0.002). This was not observed in the elderly group. Conclusions?The characteristics Abiraterone datasheet of atopy, bronchial hyperresponsiveness and lung function in elderly asthmatics are different from those in young asthmatics. This may reflect the distinct pathophysiology, at least in part, in the elderly asthmatic airway. THEERASUK KAWAMATAWONG, SUPUTTRA KHIAWWAN, SUREERAT KHANSO Division of Pulmonary and Critical Care Medicine, Ramathibodi Hospital, Bangkok, Thailand Background?Since fractional concentration of exhaled nitric oxide (FeNO) was set for monitoring of airway eosinophilic inflammation in asthma, the clinical value in real life practice has never been investigated. Materials and Methods?Cross sectional study in adult asthma patients treated at Ramathibodi Hospital between Vatalanib (PTK787) 2HCl 2012 and 2013. FeNO was measured using portable analyzer NOBREATH? (Bedford UK.). The FeNO was expressed as ppb after 10 second-exhalation through 10 cmH2O positive pressure assuring velum closure. Asthma LY2835219 manufacturer control was simultaneously assessed by Thai version asthma control test questionnaire (ACT) each visit. Data were analyzed by SPSS version 17. Results?There were 83 consecutive patients completed acceptable FeNO measurement at outpatient clinic. Mean age was 58.5?��?14.1 years. Female patients were 71.1 %. Asthma treatments were mainly ICS-LABA combination. Asthma control test score (ACT) was performed prior to physician visiting. Therefore, patients were classified as controlled asthma (ACT > 19) and uncontrolled asthma (ACT?