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Proportional hazards models were also used to model mortality and hospitalization as a function of the number of missed (or shortened) treatments in the prior month. The software SAS version 9��2 (SAS Institute, Cary, NC, USA) was utilized for all analyses. The study was approved both by the Morehouse School of Medicine Institutional Review Board and the DCI internal Review Board. Results The baseline demographic variables of the patients are shown in Table ?Table1.1. The median age of the patients was 63 years during the study period and they were followed for an average of 12.4 months per patient. The median number of years on dialysis was 1.8 years. There were 2 297 227 HD treatments of which 55 928 (2.4%) were missed treatments and 354 510 (15.4%) were shortened treatments. DCI clinics with high rates of missed treatments showed that patients who missed a treatment Ozagrel were also more likely to have high rates of shortened treatments, r = 0.53, P Galunisertib manufacturer and frequency of missed and shortened treatments is shown in Table ?Table2,2, whereas Table ?Table33 examines the effect of the dialysis schedule on missed/shortened treatments. Compared with NHWs, these non-adherence events appear to be more common among AAs, Hispanics and NAs. Missed and shortened treatments were also more prevalent in patients who dialyze on the TTS versus the MWF schedule. When individual days of the week were compared, missed treatments were more prevalent on Saturdays, Figure ?Figure1.1. There was no statistical difference in age and gender distributions between the TTS and the MWF schedules. Table 2. Comparison of the percent of treatment missed and shortened according to race/ethnicitya Table 3. Comparison of the percent of treatments missed or shortened according to the dialysis treatment schedulea Fig. 1. The percent of missed dialysis treatments by the day of the week; comparisons among all days of the week were significant (P selleckchem the effect of age on shortened treatments is shown in Table ?Table4.4. Patients aged