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The effect of platform-switching design in different tooth positions and the extent of implant-abutment mismatching were another two points of interest. Material and methods Ninty-five cases were included according to an inclusion criteria and an exclusion criteria. Fifty-four implants (Friadent, Germany) with platform-switching design were placed in 47 patients; 56 implants (Nobel Biocare, Sweden) with traditional abutment connections were placed in another 48 patients. The implants were loaded after 3�C6?months and all the crowns were utilized bonding retention. The patients were followed for 3�C5?years, during which radiographs and clinical examinations were taken to record marginal bone levels and soft-tissue remodeling respectively. The variation GS-7340 manufacturer of vertical bone height see more was calculated (positive values represented the bone increase while negative values represented bone loss). The pink esthetic scores (PES) were evaluated to assess soft tissues in esthetic areas comprehensively. Data were expressed as the mean?��?SD, t-test or ANOVA was used accordingly and a value of P?Adenylyl cyclase Ps group were 11.39?��?1.23, and 9.27?��?0.75 at the Tc group, with significant statistically differences (P?

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