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The mean age of the patient with pyogenic spondylitis and tuberculous spondylitis was 63.6 years (range 51-78 years) and 49.2 years (range 29-74 years), respectively. The mean interval from presentation to MR imaging was 7 weeks (range 1-14 weeks) in patients with pyogenic spondylitis and 26 weeks (range 1 week - 24 months) in patients with BEZ235 datasheet tuberculous spondylitis. 2. MR imaging MR imaging was performed on 1.5-T imager (Intera, Philips Medical Systems), using a surface coil or spine coil. Axial and sagittal T1-weighted MR images and fast spin-echo or turbo spin-echo T2-weighted images were obtained. In addition, axial, sagittal and coronal fat-suppressed T1-weighted images were obtained after IV infusion of 0.1mmol/kg of dimeglumine gadopentetate. Typical MR parameters were as follows: field of view, 140-280mm for axial plane, 300mm for sagittal plane and 344 mm for sagittal plane; number of excitations, 2; slice thickness, 4 mm and intersection gap, 4mm. 3. Statistical analysis Statistical analysis was 17-DMAG (Alvespimycin) HCl performed with independent two-sample T-test and ANOVA (Analysis Of Variance). RESULTS The tuberculous spondylitis (Fig. 1) group consisted of 3 males (50%) and 3 females (50%). Whereas, the pyogenic spondylitis (Fig. 2) group consisted of 10 males (58.8%) and 7 females (41.2%). The location that each spondylitis is involved is summarized in Table 1. Thoracic spine was the most common site of tuberculous spondylitis involvement. Fig. 1 A 27-year old male with tuberculous spondylitis. Angiogenesis inhibitor A: T1-weighted image (T1WI) shows heterogeneously hypointense signal in L2-3 vertebral bodies and subligamentous spread. B: T2WI shows L2-3 inhomogeneous hyperintense signal. C: Fat-suppressed contrast-enhanced ... Fig. 2 A 55 year-old male with pyogenic spondylitis. A: T1-weighted image (T1WI) shows hypointensity of L5-S1 vertebral bodies. B: T2WI shows isointese to hypointense singal of L5-S1 vertebral bodies. C: Fat-suppressed contrast-enhanced T1WI shows diffuse heterogenous ... Table 1 Site of spinal involvement The mean affected verterbra number was 2.67 (range 2-4) in tuberculous spondylitis and 2.88 (range 2-4) in pyogenic spondylitis. The results of the imaging findings for tuberculous spondylitis and pyogenic spondylits are summarized in Table 2. Table 2 MR imaging findings of tuberculous spondylitis and pyogenic spondylitis The incidence of the following MR imaging findings was singnificantly higher in patients with tuberculous spondylitis than in those with pyogenic spondylitis (p

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