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The appropriate and inappropriate antimicrobial groups were evenly distributed in the study with regard to co-morbidities and enterococcal species. An unpublished E.�coli bacteraemia study at Rigshospitalet, MI-773 conducted by the authors during the same time period, found similar co-morbidity and mortality rates (data not shown). The retrospective design of the study, and the exclusion of 28% (79/282) of the cases due to incomplete antimicrobial therapy data, could be considered limitations. While the sample size does not allow for definitive conclusions, a relevant sample of patients was included in congruence with the power calculation. In conclusion, the use of inappropriate antibiotics in the first 6�days following a case of enterococcal bacteraemia was an independent risk factor for mortality. In addition to the clinical implications, these results improve our understanding of the nature of the enterococcal bloodstream infection. It would be worthwhile to verify these results in a large, prospective study. The study received financial support from the Michaelsens Foundation (scholarship for M. Suppli). We thank Nicolai Kirkby, MSc, for helping us with the databases. We are indebted to Maria Athena Campbell Paulsen for Ribociclib molecular weight critically revising the English language. None of the authors have any conflicts of interest. ""Bloodstream infection is associated with significant short-term mortality, but less is known about long-term outcome. We describe factors affecting mortality up to 3?years after bloodstream infection in a cohort of patients reviewed at the bedside by an infection specialist. Patients seen by the bacteraemia service of our infectious diseases department between June 2005 and November 2008 were included in analyses. Routine clinical data collected at the time of consultation, Otenabant together with laboratory, demographic and outcome data were analysed to identify factors predicting death at 30?days and 3?years after bloodstream infection. Cox regression models for both time-points were constructed, together with Kaplan�CMeier survival curves. In all, 322 bloodstream infections were recorded in 304 patients. The 30-day mortality was 15%, with a 3-year mortality of 49%. At 30?days after bacteraemia, in the Cox regression model, increasing age (p 0.003) and lower serum albumin (p 0.014) were predictive of death. At 3?years, age (p?
