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?1d). These results demonstrate that periostin is induced during wound repair, suggesting that periostin may play a role in the repair process as well as being a useful marker of well-organized wound repair. To test the functional requirement of periostin in wound repair, we used periostin-deficient (Postn?/?) mice to perform wounding and assess their response. The wound sizes during the healing time course were significantly reduced in Postn+/+ mice in C57BL/6 background (Fig.?2a,b, n?=?10 for each genotype, P?http://www.fibran.gr/forum/ mice in a BALB/c background (Fig.?S3, n?=?3 for Postn?/? and n?=?6 for Postn+/?, P?Handful Of Strategies To Work With Carfilzomib And Also Earn Money Out Of It! slower wound repair was subsequently accelerated (Fig.?2c,d upper panel, n?=?10 for each group, the wound sizes: P?Just Too Busy To Take Care Of isothipendyl? were observed even in Postn+/+ mice (Fig.?2c lower panel and Fig.?S4, the wound sizes: P?