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Total costs for post-burn treatment were assessed ��per case�� or episode, e.g. several readmissions for one single patient counted separately. To account for individual costs ��per patient��, treatment costs for multiple readmissions INSRR and interventions at different time periods were added and stated as cost per individual patient. Patients�� files were screened for scarring and other post-burn sequelae. Burn patient questionnaire Treatment costs for aftercare and occurrence of burn scars were assessed by an anonymous questionnaire (Annex II) that was sent to patients with previous treatment in the Burn Centre between 2006 and 2009. Among other information, data on total burned body surface area, burned body parts, aftercare, scar formation with or without need for readmission and surgery were retrieved. Statement of scar formation was provided by patients without further physical examination. Therefore, no detailed data on type of scarring, e.g. hypertrophic scarring, could be gained from this data source. Post-burn scarring leading to surgical procedures was interpreted as pathological, e.g. excessive scarring. In Germany, costs for medical care are covered by public health care providers (90%), private insurances (ca 9%) and workmen compensation funds, without the need for patients to directly pay for prescriptions BLZ945 or hospital stays. Therefore, exact prices for pressure garments, creams or pain killers could not be stated by patients but rather amounts of items or substances used during the treatment period. In order to estimate total costs, the lowest price for each particular item was used for cost calculation, e.g. 400 EUR per pressure garment, 10 EUR per 50g tube of cream, 25 EUR per silicone sheet, and 15 EUR per package of analgetic medication (30 pills). Costs were adjusted if specific prices or brands were stated in the questionnaire. Although G-DRG assessment and patient survey were conducted during the same time period, data could not be linked or compared due to anonymous data sampling. selleck chemicals Statistics Two-tailed Student��s t-test for paired observations was applied when normal distribution was assumed. The Wilcoxon Signed Rank test was used for paired observations when normal distribution did not apply, using the software MATLAB? (version 7.12.0.635 (R2011a); The MathWorks Inc, Natick, MA, USA). P