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[10] If sputum purulence is associated with proteolytic activity and bacterial infection, and this links to disease progression, what can we offer for the patient with green sputum? An increasing number of therapies are becoming available in bronchiectasis with evidence now supporting the use of oral macrolides, inhaled antibiotics and other therapies. Antibiotic therapy is highly effective in reducing both proteolytic activity and clearing sputum colour.[5] Stratifying patients to identify those at risk of disease progression requiring prolonged antibiotic or anti-inflammatory therapies is vital, while keeping in mind the potential side effects and the threat of antimicrobial resistance selleck chemical that accompany these treatments. Until better biomarkers are available, sputum colour is our only direct measure of airway Mianserin HCl inflammation in routine practice��the original biomarker, and should be part of a global assessment of which patients require aggressive treatment. ""4879" "Internet addiction (IA) is both the most rapidly growing addiction and the least understood addiction (Watson, 2005). For counselors, treatment issues surrounding the disease are also growing. At the forefront is the lack of understanding concerning treatment protocol to manage the challenging recovery and maintenance stages after IA behavior has been controlled. The authors discuss Viktor Frankl's logotherapy as an effective approach to treating IA. ""4880" "A combined pulmonary fibrosis/emphysema syndrome has been proposed, but the basis for this syndrome is currently uncertain. The aim was to evaluate the prevalence of emphysema in idiopathic pulmonary fibrosis (IPF) and rheumatoid lung (rheumatoid arthritis-interstitial lung disease (RA-ILD)), and to compare the morphological features of lung fibrosis between smokers and non-smokers. Using high-resolution computed tomography, the prevalence of emphysema and the pack-year smoking histories associated with emphysema were compared between current/ex-smokers with IPF (n?=?186) or RA-ILD (n?=?46), and non-chronic obstructive pulmonary disease (COPD) controls (n?=?103) and COPD controls (n?=?34). The coarseness of fibrosis was compared between smokers and non-smokers. Emphysema, present in 66/186 (35%) patients with IPF and 22/46 (48%) smokers with RA-ILD, selleck was associated with lower pack-year smoking histories than in control groups (P?
