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The first six-month CR cycle, analogical to the observation conducted for the entire test group, led to a statistically significant increase in the mean HRR60 value. However, continuation of the CR in accordance with the same model no longer led to a further improvement in the HRR60 intensity. Therefore, extension of training duration over 6 months allows to maintain the obtained results, however it does not increase them any further. In the analysis of the modifying impact of rehabilitation exercises (carried out according to many schedules) on vagus nerve tension, a question arises whether the obtained effects might be dependent on intensity of the applied cardiac training. Moholdt et al. [ 22] compared the impact of various CR models on HRR60 in 107 patients after myocardial infarction. They analyzed the effects evoked by classical CR Afatinib chemical structure and AIT (aerobic interval treadmill) rehabilitation, in which exercises lasted 4��4 minutes and led to obtaining 85�C95% of max HR. It was considered that the new rehabilitation technique, compared to classical CR, does not affect significantly differently the change in the HRR60 value. Importance of the impact of additional physical activity accompanying a CR cycle on HRR dynamics was examined by Sato et al. [ 11] HRR assessment was conducted on the day when the examination was initiated and after 2 weeks of Dasatinib purchase CR. After termination of CR, the time of HRR changed only in the more active group pPTPRJ Pearson's coefficient r=?0.595, only with the initial HRR60 intensity This testifies to the statement that patients who start training with the lowest heart rate recovery adaptation dynamics achieve the greatest increment of it as a result of CR. A graph illustrating the linear relationship between ��HRR60 and the initial HRR60 value is presented in Fig. 2. The grade of HRR dynamic change (��HRR60) is not affected by cardiac training intensity assessed by means of initial, final and mean cardiac training work or by the increment of their work within 6 months of a CR cycle. Maintaining the beneficial effect of CR also seems to be a key issue. It was analyzed by Giallauria et al. [ 23] who observed a group of 44 patients after myocardial infarction subjected to a three-month CR. As might be expected given other observations concerning the positive effects of physical activity, maintaining HRR60 improvement also required further continuation of the cardiac training. Studies performed on populations of IHD patients using different training procedures complement the knowledge about the process of post-exertion heart rate restitution.