Epacadostat: An Impeccable Advantage!

92, P?=?0.001], and self-report of being in good/excellent health (OR 2.39, P?=?0.005). When post-bronchodilator FEV1 was added to the analysis, undiagnosed disease was predicted by pack years [OR 1.21 (1.01�C1.47) per 10 pack-year increase, P?=?0.043], and close to normal lung function [OR 1.48 (1.22�C1.80) per 10% increase in post-bronchodilator FEV1 % predicted, P? MG132 and cardiac co-morbidity were not associated with having undiagnosed COPD. Conclusion:? Two out of three COPD patients in Norway are undiagnosed. Risk factors for being undiagnosed are moderate reduction in lung function, absence of COPD symptoms and self-report of being in good health. Please cite this paper as: Hvidsten SC, Storesund L, Wentzel-Larsen T, Gulsvik A and Lehmann S. Prevalence and predictors of undiagnosed ATPase chronic obstructive pulmonary disease in a Norwegian adult general population. The Clinical Respiratory Journal 2009; DOI:10.1111/j.1752-699X.2009.00137.x. ""Asthma control and quality of life are poorly associated with traditional asthma biomarkers. In the present study, we evaluated two new cough provocation tests in this respect. Asthma Control Questionnaire and Leicester Cough Questionnaire were completed by 36 stable asthmatics. Cough provocation tests with hypertonic saline and isocapnic hyperpnoea of dry air were performed, as well as spirometry, ambulatory peak expiratory flow (PEF) monitoring and exhaled nitric oxide (eNO) measurement. Leicester Cough Questionnaire score correlated closely with cough responsiveness find more to hypertonic saline and isocapnic hyperpnoea (R?=??0.66, P?