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For comparison of non ulcerative lesions we excluded the segments that contained superficial or deep ulcerations as well, as they are not separately scored in the CDEIS. When comparing disease duration, with DCE-data only the segment with the highest ME and ISI was used. To minimize clustering effect we used non parametric testing and give median values. Statistical analysis was performed by using software INCB018424 PASW statistics 18 (Chicago, IL, USA). A p-value AZ191 13 purine-antagonists (39%), six steroids (18%) and 10 anti-tumour necrosis factor (30%). Sixteen patients (49%) previously underwent an ileocecal resection. Twenty segments (12%) were of insufficient quality due to suboptimal distension and/or suboptimal contrast between lumen and bowel wall to be used for grading. In total 144 (89%) segments could be evaluated. It was always possible to include all visible inflamed bowel segments in the DCE-ROI. All data except ISI, enhancement ratio and T2 signal intensity ratio were not normally distributed. The median time between colonoscopy and MRI was 8 days (IQR 6�C16). MRI and colonoscopy was not performed one the same day. Median CDEIS was 4.4 (IQR 1.6�C6.9). Median segmental CDEIS was 0 (IQR 4.5). Median CDAI was 141 (IQR 81�C226). Median CRP was 6 (IQR 1�C22), median disease duration 10 years (6�C14). Wall thickness was weakly correlated with segmental CDEIS (r?=?0.418, p?PF-02341066 supplier 3). The subjective assessment of T2 signal intensity was significantly associated with segmental CDEIS (p?