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5 mU/L in the first trimester and Hesperadin 27% targeted TSH and FT4 within trimester-specific reference ranges, and 10% and 23% targeted TSH and FT4 within laboratory reference ranges, for endocrinologists and generalists, respectively, P = 0.001 (Supplement 3). 4.5. Screening Pregnant Women for Thyroid Dysfunction For no systematic screening, targeted screening of pregnant women at high risk of thyroid dysfunction and universal screening of all pregnant women, endocrinologists voted 11, 73 and 16%, respectively, while the corresponding values for generalists were 21, 52 and 29% (P TSH and FT4 or TT4. More endocrinologists than generalists ABT-737 purchase order thyroid antibodies (P replacement, following the screening, Torin 1 ic50 they indicated the following criteria, respectively: 53% and 36% would start at a TSH above the trimester-specific reference range; 1% and 11% at a TSH above the population reference range; 325 and 39% at a TSH > 2.5 ?mU/L; 10% and 11% at a TSH > 5 ?mU/L, and 4% and 3% at a FT4 below the trimester-specific reference range. Responders�� approaches to various outcomes of screening thyroid function in pregnancy differed (Figure 1): 43% of endocrinologists and 18% of generalists would treat isolated hypothyroxinemia (P = 0.012); 52% and 53% would treat isolated positive thyroid antibodies with normal TSH, respectively; 61% and 49% would treat TSH level >2.5 (and 2.5 (and