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05) increased in the Control group, but not in the N. sativa group. Table 3 Changes in echocardiographic measurements of LV internal dimensions at different treatment durations in the control group and N. sativa group [http://www.selleckchem.com/products/icotinib.html Icotinib] compared to their corresponding baseline values Table 4 demonstrates a comparison of all the echocardiographic parameters between the control group and N. sativa group at the baseline, 6 months and 12 months after initiation of treatment. There was no significant difference in any baseline reading for all echocardiographic parameters evaluated. LVIDs at 6th month were significantly (P [http://en.wikipedia.org/wiki/YES1 YES1] (MAP) between baseline, 6 months and 12 months for both the groups. HbA1c was reduced in the N. sativa group at both follow-ups; but, this reduction was only significant at 12 months (P [http://www.selleckchem.com/products/Thiazovivin.html Selleckchem Thiazovivin] on cardiac diastolic and systolic functions and LVM in diabetic patients. N. sativa supplementation tended to prevent diastolic dysfunction as well as improve systolic function. In addition, it showed a trend of preventing an increase in the LVM. Cardiac dysfunction in patients with DM manifests as diabetic cardiomyopathy that is characterized by an early diastolic and late systolic dysfunction.[6,7] Diastolic dysfunction has been reported in diabetic animals[19] as well as diabetic patients.[20,21] Transmitral flow (E/A) ratio as a marker of diastolic dysfunction has been found to be impaired in diabetic patients without overt cardiovascular disease.[22,23] In this study, the placebo group showed a trend towards diastolic dysfunction, as E/A ratio was significantly decreased at the end of the study, while in N. sativa group, the diastolic function was preserved. This may imply a protective role of N. sativa against diastolic dysfunction in diabetic patients. Left ventricular systolic dysfunction has been linked to DM as a late manifestation of diabetic cardiomyopathy.

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Goldferry8 : Page créée avec « 05) increased in the Control group, but not in the N. sativa group. Table 3 Changes in echocardiographic measurements of LV internal dimensions at different treatment dura... »