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8 Infants were classified according to the birth weight into Group 1 who were [http://www.selleckchem.com/products/Dasatinib.html BMS-354825 research buy] Redmond, WA, USA). The data were transferred to Statistical Package for Social Studies (SPSS 22) (IBM, Chicago, USA) for analysis. Univariate analysis was performed using a parametric method for calculating frequencies and percentage proportions of qualitative variables. For continuous variables mean and standard deviations were calculated. To compare ROP risk in subgroups, Odd's ratio and the 95% confidence interval (CI) were calculated. A two-sided P  RESULTS The study population included 1829 premature infants of which 1795 (98.6%) infants were included in the study because their data in the patient charts were complete. There were 700 [38.9%]) infants in Group 1 and 1095 [61.1%]) infants in Group II. ROP at any stage was detected in 367 of 1795 infants. This leads to an incidence of 20.4%. Stage III ROP was detected in 68/1795 (3.8%) infants and represents 18.5% of [http://www.selleckchem.com/products/s-gsk1349572.html GSK1349572 research buy] the total number of ROP cases. Stage III threshold disease requiring laser retinal photocoagulation was detected in 21/367 (5.7%) infants, and 5/367 (1.4%) infants progressed to stage IV ROP which required vitreoretinal surgery. Eighty percent (293/367) of the ROP cases occurred in neonates with BW  incidence of any ROP among all newborn infants in Bahrain during the study period was 1/434 (0.2%) infants. Mean gestational age and birth weight were significantly lower among infants with ROP [Table 3].9 Table 3 Distribution of live births per year in [http://en.wikipedia.org/wiki/SAR1B SAR1B] the national registry and premature infants in Bahrain and at the SMC DISCUSSION Our study represents the incidence of ROP in the largest study population in Bahrain to date. It comprises 75% of the deliveries in Bahrain. The incidence of ROP in previous studies varies by region from 22% to 56% [Table 4].10,11,12,13,14,15,16 The incidence of ROP in the current study is similar to previous reports. However, comparison to other studies is tenuous at best as some studies included neonates with a birth weight